Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress

Type 2 diabetes mellitus (T2DM) results from pancreatic β cell failure in the setting of insulin resistance. Heterozygous mutations in the gene encoding the β cell transcription factor pancreatic duodenal homeobox 1 (Pdx1) are associated with both T2DM and maturity onset diabetes of the young (MODY4...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Sachdeva, Mira M., Claiborn, Kathryn C., Khoo, Cynthia, Yang, Juxiang, Groff, David N., Mirmira, Raghavendra G., Stoffers, Doris A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2009
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776433/
https://ncbi.nlm.nih.gov/pubmed/19855005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904849106
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items