The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice

Heterozygous mutations in the gene encoding the pancreatic homeodomain transcription factor pancreatic duodenal homeobox 1 (PDX1) are associated with maturity onset diabetes of the young, type 4 (MODY4) and type 2 diabetes. Pdx1 governs the early embryonic development of the pancreas and the later d...

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Bibliografische gegevens
Hoofdauteurs: Oliver-Krasinski, Jennifer M., Kasner, Margaret T., Yang, Juxiang, Crutchlow, Michael F., Rustgi, Anil K., Kaestner, Klaus H., Stoffers, Doris A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2009
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701861/
https://ncbi.nlm.nih.gov/pubmed/19487809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI37028
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