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The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice
Heterozygous mutations in the gene encoding the pancreatic homeodomain transcription factor pancreatic duodenal homeobox 1 (PDX1) are associated with maturity onset diabetes of the young, type 4 (MODY4) and type 2 diabetes. Pdx1 governs the early embryonic development of the pancreas and the later d...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2701861/ https://ncbi.nlm.nih.gov/pubmed/19487809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI37028 |
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