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The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice

Heterozygous mutations in the gene encoding the pancreatic homeodomain transcription factor pancreatic duodenal homeobox 1 (PDX1) are associated with maturity onset diabetes of the young, type 4 (MODY4) and type 2 diabetes. Pdx1 governs the early embryonic development of the pancreas and the later d...

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Bibliografske podrobnosti
Main Authors: Oliver-Krasinski, Jennifer M., Kasner, Margaret T., Yang, Juxiang, Crutchlow, Michael F., Rustgi, Anil K., Kaestner, Klaus H., Stoffers, Doris A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701861/
https://ncbi.nlm.nih.gov/pubmed/19487809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI37028
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