Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress

Type 2 diabetes mellitus (T2DM) results from pancreatic β cell failure in the setting of insulin resistance. Heterozygous mutations in the gene encoding the β cell transcription factor pancreatic duodenal homeobox 1 (Pdx1) are associated with both T2DM and maturity onset diabetes of the young (MODY4...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sachdeva, Mira M., Claiborn, Kathryn C., Khoo, Cynthia, Yang, Juxiang, Groff, David N., Mirmira, Raghavendra G., Stoffers, Doris A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2009
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776433/
https://ncbi.nlm.nih.gov/pubmed/19855005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904849106
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak