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Effect of N-acetylcysteine route of administration on chemoprotection against cisplatin-induced toxicity in rat models
Dosing and route of administration of N-acetylcysteine (NAC) for protection against cisplatin (CDDP) nephrotoxicity was investigated in rats. Two models of toxicity were tested: a single high dose of CDDP (10 mg/kg intraperitoneally (IP)), and multiple low dose treatments (1 mg/kg IP twice a day for...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2776068/ https://ncbi.nlm.nih.gov/pubmed/17909806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-007-0597-2 |
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