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N-acetylcysteine chemoprotection without decreased cisplatin antitumor efficacy in pediatric tumor models
BACKGROUND: Decreasing oxidative damage with the antioxidant agent N-acetylcysteine (NAC) can block the side effects of chemotherapy, but may diminish anti-tumor efficacy. We tested the potential for interactions of high dose NAC against a minimally effective cisplatin chemotherapy regimen in rat mo...
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| Publicado no: | J Neurooncol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4324166/ https://ncbi.nlm.nih.gov/pubmed/25411097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-014-1657-1 |
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