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Imaging and therapy with rituximab anti-CD20 immunotherapy in an animal model of central nervous system lymphoma

PURPOSE: To evaluate the effect of rituximab monoclonal antibody (mAb) on magnetic resonance imaging (MRI) tumor volumetrics and efficacy in a rat model of central nervous system (CNS) lymphoma when delivery to the brain was optimized with osmotic blood-brain barrier disruption (BBBD). EXPERIMENTAL...

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Detalhes bibliográficos
Main Authors: Muldoon, Leslie L., Lewin, Seth J., Dósa, Edit, Kraemer, Dale F., Pagel, Michael A., Doolittle, Nancy D., Neuwelt, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337144/
https://ncbi.nlm.nih.gov/pubmed/21385922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2923
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