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Cutting Edge: Lipopolysaccharide Induces IL-10-Producing Regulatory CD4(+) T Cells That Suppress the CD8(+) T Cell Response

TLR ligands are potent activators of dendritic cells and therefore function as adjuvants for the induction of immune responses. We analyzed the capacity of TLR ligands to enhance CD8(+) T cell responses toward soluble protein Ag. Immunization with OVA together with LPS or poly(I:C) elicited weak CD8...

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Autors principals: den Haan, Joke M. M., Kraal, Georg, Bevan, Michael J.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776046/
https://ncbi.nlm.nih.gov/pubmed/17442923
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