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Cutting Edge: Regulatory T Cells Directly Suppress B Cells in Systemic Lupus Erythematosus

In systemic lupus erythematosus (SLE), adaptive CD4(+)CD25(+)Foxp3(+) regulatory T cells (Tregs) suppress Th cells that help autoantibody (autoAb)-producing B cells. It is not known whether naturally occurring Tregs can directly suppress B cells in SLE without an intermediate suppression of Th cells...

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Main Authors: Iikuni, Noriko, Lourenço, Elaine V., Hahn, Bevra H., La Cava, Antonio
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730469/
https://ncbi.nlm.nih.gov/pubmed/19570829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901163
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