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Dendritic cells license regulatory B cells to produce IL-10 and mediate suppression of antigen-specific CD8 T cells

Regulatory B cells (Bregs) suppress and reduce autoimmune pathology. However, given the variety of Breg subsets, the role of Bregs in the pathogenesis of type 1 diabetes is still unclear. Here, we dissect this fundamental mechanism. We show that natural protection from type 1 diabetes in nonobese di...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Boldison, Joanne, Da Rosa, Larissa Camargo, Davies, Joanne, Wen, Li, Wong, F. Susan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7395736/
https://ncbi.nlm.nih.gov/pubmed/31728048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-019-0324-z
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