Early-Onset and Robust Amyloid Pathology in a New Homozygous Mouse Model of Alzheimer's Disease

BACKGROUND: Transgenic mice expressing mutated amyloid precursor protein (APP) and presenilin (PS)-1 or -2 have been successfully used to model cerebral β-amyloidosis, one of the characteristic hallmarks of Alzheimer's disease (AD) pathology. However, the use of many transgenic lines is limited...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Willuweit, Antje, Velden, Joachim, Godemann, Robert, Manook, Andre, Jetzek, Fritz, Tintrup, Hartmut, Kauselmann, Gunther, Zevnik, Branko, Henriksen, Gjermund, Drzezga, Alexander, Pohlner, Johannes, Schoor, Michael, Kemp, John A., von der Kammer, Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775952/
https://ncbi.nlm.nih.gov/pubmed/19936202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007931
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados