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Lipopolysaccharide directly alters renal tubule transport through distinct TLR4-dependent pathways in basolateral and apical membranes

Bacterial infection of the kidney is associated with renal tubule dysfunction and dysregulation of systemic electrolyte balance. Whether bacterial molecules directly affect renal tubule transport is unknown. We examined the effects of LPS on HCO(3)(−) absorption in the isolated rat and mouse medulla...

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Detalhes bibliográficos
Main Authors: Good, David W., George, Thampi, Watts, Bruns A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775577/
https://ncbi.nlm.nih.gov/pubmed/19625374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00335.2009
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