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AMPA Receptor Ligand Binding Domain Mobility Revealed by Functional Cross Linking

Glutamate receptors mediate the majority of excitatory synaptic transmission in the CNS. The AMPA-subtype has rapid kinetics, with activation, deactivation and desensitization proceeding on the millisecond timescale or faster. Crystallographic, biochemical, and functional studies suggest that GluR2...

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Détails bibliographiques
Auteurs principaux: Plested, Andrew J. R., Mayer, Mark L.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775448/
https://ncbi.nlm.nih.gov/pubmed/19776277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2971-09.2009
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