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Immediate mediators of the inflammatory response are poised for gene activation through RNA polymerase II stalling
The kinetics and magnitude of cytokine gene expression are tightly regulated to elicit a balanced response to pathogens and result from integrated changes in transcription and mRNA stability. Yet, how a single microbial stimulus induces peak transcription of some genes (TNFα) within minutes whereas...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2775335/ https://ncbi.nlm.nih.gov/pubmed/19820169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910177106 |
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