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RNA Polymerase Stalling at Developmental Control Genes in the Drosophila Embryo

It is widely assumed that the key rate-limiting step in gene activation is the recruitment of RNA polymerase II (Pol II) to the core promoter2. Although there are well-documented examples where Pol II is recruited to a gene but stalls3–14, a general role for Pol II stalling in development has not be...

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Detalhes bibliográficos
Main Authors: Zeitlinger, Julia, Stark, Alexander, Kellis, Manolis, Hong, Joung-Woo, Nechaev, Sergei, Adelman, Karen, Levine, Michael, Young, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824921/
https://ncbi.nlm.nih.gov/pubmed/17994019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2007.26
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