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Protein Kinase A and B-Raf Mediate Extracellular Signal-Regulated Kinase Activation by Thyrotropin

Thyrotropin (TSH) regulates thyroid cell proliferation and function through cAMP-mediated signaling pathways that activate protein kinase A (PKA) and Epac/Rap1. The respective roles of PKA versus Epac/Rap1 in TSH signaling remain unclear. We set out to determine whether PKA and/or Rap1 mediate extra...

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Detaylı Bibliyografya
Asıl Yazarlar: Vuchak, Lisa A., Tsygankova, Oxana M., Prendergast, Gregory V., Meinkoth, Judy L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Pharmacology and Experimental Therapeutics 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774990/
https://ncbi.nlm.nih.gov/pubmed/19720729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.060129
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