Identification of Novel In Vivo Raf-1 Phosphorylation Sites Mediating Positive Feedback Raf-1 Regulation by Extracellular Signal-regulated Kinase

The Ras–Raf–mitogen-activated protein kinase cascade is a key growth-signaling pathway, which uncontrolled activation results in transformation. Although the exact mechanisms underlying Raf-1 regulation remain incompletely understood, phosphorylation has been proposed to play a critical role in this...

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Autores principales: Balan, Vitaly, Leicht, Deborah T., Zhu, Jun, Balan, Karina, Kaplun, Alexander, Singh-Gupta, Vinita, Qin, Jun, Ruan, Hong, Comb, Michael J., Tzivion, Guri
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2006
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1382304/
https://ncbi.nlm.nih.gov/pubmed/16407412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-12-1123
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