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A-Raf and B-Raf Are Dispensable for Normal Endochondral Bone Development, and Parathyroid Hormone-Related Peptide Suppresses Extracellular Signal-Regulated Kinase Activation in Hypertrophic Chondrocytes

Parathyroid hormone-related peptide (PTHrP) and the parathyroid hormone-PTHrP receptor increase chondrocyte proliferation and delay chondrocyte maturation in endochondral bone development at least partly through cyclic AMP (cAMP)-dependent signaling pathways. Because data suggest that the ability of...

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Detalles Bibliográficos
Main Authors: Provot, Sylvain, Nachtrab, Gregory, Paruch, Jennifer, Chen, Adele Pin, Silva, Alcino, Kronenberg, Henry M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2223319/
https://ncbi.nlm.nih.gov/pubmed/17967876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00617-07
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