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Constriction of Carotid Arteries by Urokinase-Type Plasminogen Activator Requires Catalytic Activity and is Independent of NH(2)-Terminal Domains

Urokinase-type plasminogen activator (uPA) is expressed at increased levels in stenotic, atherosclerotic human arteries. However, the biological roles of uPA in the artery wall are poorly understood. Previous studies associate uPA with both acute vasoconstriction and chronic vascular remodeling and...

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Detalhes bibliográficos
Main Authors: Massey, Philip G., Tanaka, Shinji, Buckler, Joshua M., Jiang, Bo, McCourtie, Anton, Qian, Kun, Tom, Clifford, Stempien-Otero, April, Wen, Shan, Luttrell, Ian, Chitaley, Kanchan, Dichek, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774917/
https://ncbi.nlm.nih.gov/pubmed/19888538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH09-03-0161
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