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The Role of Macrophage Derived Urokinase Plasminogen Activator in Myocardial Infarct Repair: Urokinase Attenuates Ventricular Remodeling

Cardiac plasmin activity is increased following myocardial ischemia. To test the hypothesis that macrophage-derived uPA is a key mediator of repair following myocardial infarction we performed myocardial infarction on mice with macrophage specific over-expression of uPA (SR-uPA mice). SR-uPA(+/0) mi...

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Bibliographische Detailangaben
Hauptverfasser: Minami, Elina, Castellani, Chiara, Malchodi, Laura, Deem, Jennifer, Bertko, Kate, Meznarich, Jessica, Dishmon, Monja, Murry, Charles E., Stempien-Otero, April
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041515/
https://ncbi.nlm.nih.gov/pubmed/20380835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2010.03.022
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