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Functional Effects of a Restrictive Cardiomyopathy linked Cardiac Troponin I mutation (R145W) in Transgenic Mice

The human cardiac troponin I (hcTnI) mutation, R145W, has been associated with restrictive cardiomyopathy. In this study, simultaneous measurements of ATPase activity and force in transgenic skinned papillary fibers from hcTnI R145W transgenic mice (Tg-R145W) were explored. The Tg-R145W fibers showe...

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Detalhes bibliográficos
Main Authors: Wen, Yuhui, Xu, Yuanyuan, Wang, Yingcai, Pinto, Jose Renato, Potter, James D., Kerrick, W. Glenn L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774805/
https://ncbi.nlm.nih.gov/pubmed/19651143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.07.080
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