Functional Consequences of the Human Cardiac Troponin I Hypertrophic Cardiomyopathy Mutation R145G in Transgenic Mice

In this study, we addressed the functional consequences of the human cardiac troponin I (hcTnI) hypertrophic cardiomyopathy R145G mutation in transgenic mice. Simultaneous measurements of ATPase activity and force in skinned papillary fibers from hcTnI R145G transgenic mice (Tg-R145G) versus hcTnI w...

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Main Authors: Wen, Yuhui, Pinto, Jose Renato, Gomes, Aldrin V., Xu, Yuanyuan, Wang, Yingcai, Wang, Ying, Potter, James D., Kerrick, W. Glenn L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Protein Structure and Folding
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2459290/
https://ncbi.nlm.nih.gov/pubmed/18430738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801661200
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