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A Functional and Structural Study of Troponin C Mutations Related to Hypertrophic Cardiomyopathy

Recently four new hypertrophic cardiomyopathy mutations in cardiac troponin C (cTnC) (A8V, C84Y, E134D, and D145E) were reported, and their effects on the Ca(2+) sensitivity of force development were evaluated (Landstrom, A. P., Parvatiyar, M. S., Pinto, J. R., Marquardt, M. L., Bos, J. M., Tester,...

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Detalhes bibliográficos
Main Authors: Pinto, Jose Renato, Parvatiyar, Michelle S., Jones, Michelle A., Liang, Jingsheng, Ackerman, Michael J., Potter, James D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707221/
https://ncbi.nlm.nih.gov/pubmed/19439414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.007021
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