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Evolutionary constraints on structural similarity in orthologs and paralogs

Although a quantitative relationship between sequence similarity and structural similarity has long been established, little is known about the impact of orthology on the relationship between protein sequence and structure. Among homologs, orthologs (derived by speciation) more frequently have simil...

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Detalhes bibliográficos
Main Authors: Peterson, Mark E, Chen, Feng, Saven, Jeffery G, Roos, David S, Babbitt, Patricia C, Sali, Andrej
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774440/
https://ncbi.nlm.nih.gov/pubmed/19472362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.143
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