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The ortholog conjecture revisited: the value of orthologs and paralogs in function prediction

MOTIVATION: The computational prediction of gene function is a key step in making full use of newly sequenced genomes. Function is generally predicted by transferring annotations from homologous genes or proteins for which experimental evidence exists. The ‘ortholog conjecture’ proposes that ortholo...

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Bibliografiske detaljer
Udgivet i:Bioinformatics
Main Authors: Stamboulian, Moses, Guerrero, Rafael F, Hahn, Matthew W, Radivojac, Predrag
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355290/
https://ncbi.nlm.nih.gov/pubmed/32657391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa468
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