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The ortholog conjecture revisited: the value of orthologs and paralogs in function prediction

MOTIVATION: The computational prediction of gene function is a key step in making full use of newly sequenced genomes. Function is generally predicted by transferring annotations from homologous genes or proteins for which experimental evidence exists. The ‘ortholog conjecture’ proposes that ortholo...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Stamboulian, Moses, Guerrero, Rafael F, Hahn, Matthew W, Radivojac, Predrag
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355290/
https://ncbi.nlm.nih.gov/pubmed/32657391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa468
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