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Functional prediction: identification of protein orthologs and paralogs.

Orthologs typically retain the same function in the course of evolution. Using beta-decarboxylating dehydrogenase family as a model, we demonstrate that orthologs can be confidently identified. The strategy is based on our recent findings that substitutions of only a few amino acid residues in these...

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Hlavní autoři: Chen, R., Jeong, S. S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144510/
https://ncbi.nlm.nih.gov/pubmed/11206056
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