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Functional prediction: identification of protein orthologs and paralogs.

Orthologs typically retain the same function in the course of evolution. Using beta-decarboxylating dehydrogenase family as a model, we demonstrate that orthologs can be confidently identified. The strategy is based on our recent findings that substitutions of only a few amino acid residues in these...

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Detalhes bibliográficos
Main Authors: Chen, R., Jeong, S. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144510/
https://ncbi.nlm.nih.gov/pubmed/11206056
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