The Bacterial Defensin Resistance Protein MprF Consists of Separable Domains for Lipid Lysinylation and Antimicrobial Peptide Repulsion

Many bacterial pathogens achieve resistance to defensin-like cationic antimicrobial peptides (CAMPs) by the multiple peptide resistance factor (MprF) protein. MprF plays a crucial role in Staphylococcus aureus virulence and it is involved in resistance to the CAMP-like antibiotic daptomycin. MprF is...

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Main Authors: Ernst, Christoph M., Staubitz, Petra, Mishra, Nagendra N., Yang, Soo-Jin, Hornig, Gabriele, Kalbacher, Hubert, Bayer, Arnold S., Kraus, Dirk, Peschel, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774229/
https://ncbi.nlm.nih.gov/pubmed/19915718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000660
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