Calmodulin kinase II initiates arrhythmogenicity during metabolic acidification in murine hearts

AIM: The multifunctional signal molecule calmodulin kinase II (CaMKII) has been associated with cardiac arrhythmogenesis under conditions where its activity is chronically elevated. Recent studies report that its activity is also acutely elevated during acidosis. We test a hypothesis implicating CaM...

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Détails bibliographiques
Auteurs principaux: Pedersen, T H, Gurung, I S, Grace, A, Huang, C L-H
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2009
Sujets:
Cardiovascular
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774152/
https://ncbi.nlm.nih.gov/pubmed/19416122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1748-1716.2009.01991.x
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