Calmodulin kinase II initiates arrhythmogenicity during metabolic acidification in murine hearts

AIM: The multifunctional signal molecule calmodulin kinase II (CaMKII) has been associated with cardiac arrhythmogenesis under conditions where its activity is chronically elevated. Recent studies report that its activity is also acutely elevated during acidosis. We test a hypothesis implicating CaM...

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Main Authors: Pedersen, T H, Gurung, I S, Grace, A, Huang, C L-H
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2009
Assuntos:
Cardiovascular
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774152/
https://ncbi.nlm.nih.gov/pubmed/19416122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1748-1716.2009.01991.x
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