Calmodulin kinase II initiates arrhythmogenicity during metabolic acidification in murine hearts

AIM: The multifunctional signal molecule calmodulin kinase II (CaMKII) has been associated with cardiac arrhythmogenesis under conditions where its activity is chronically elevated. Recent studies report that its activity is also acutely elevated during acidosis. We test a hypothesis implicating CaM...

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Main Authors: Pedersen, T H, Gurung, I S, Grace, A, Huang, C L-H
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2009
Teme:
Cardiovascular
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774152/
https://ncbi.nlm.nih.gov/pubmed/19416122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1748-1716.2009.01991.x
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