A quantitative analysis of the effect of cycle length on arrhythmogenicity in hypokalaemic Langendorff-perfused murine hearts

The clinically established proarrhythmic effect of bradycardia and antiarrhythmic effect of lidocaine (10 μM) were reproduced in hypokalaemic (3.0 mM K(+)) Langendorff-perfused murine hearts paced over a range (80–180 ms) of baseline cycle lengths (BCLs). Action potential durations (at 90% repolariz...

Full description

Saved in:
Bibliographic Details
Main Authors: Sabir, Ian N., Fraser, James A., Cass, Thomas R., Grace, Andrew A., Huang, Christopher L.-H.
Format: Artigo
Language:Inglês
Published: Springer-Verlag 2007
Subjects:
Cardiovascular System
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2627988/
https://ncbi.nlm.nih.gov/pubmed/17437126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-007-0255-x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items