A quantitative analysis of the effect of cycle length on arrhythmogenicity in hypokalaemic Langendorff-perfused murine hearts

The clinically established proarrhythmic effect of bradycardia and antiarrhythmic effect of lidocaine (10 μM) were reproduced in hypokalaemic (3.0 mM K(+)) Langendorff-perfused murine hearts paced over a range (80–180 ms) of baseline cycle lengths (BCLs). Action potential durations (at 90% repolariz...

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Autores principales: Sabir, Ian N., Fraser, James A., Cass, Thomas R., Grace, Andrew A., Huang, Christopher L.-H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer-Verlag 2007
Materias:
Cardiovascular System
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2627988/
https://ncbi.nlm.nih.gov/pubmed/17437126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-007-0255-x
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