Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/− murine hearts modelling the Brugada syndrome

Brugada syndrome (BrS) is associated with a loss of Na(+) channel function and an increased incidence of rapid polymorphic ventricular tachycardia (VT) and sudden cardiac death. A programmed electrical stimulation (PES) technique assessed arrhythmic tendency in Langendorff-perfused wild-type (WT) an...

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Detalhes bibliográficos
Main Authors: Stokoe, Kate S, Balasubramaniam, Richard, Goddard, Catharine A, Colledge, William H, Grace, Andrew A, Huang, Christopher L-H
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075209/
https://ncbi.nlm.nih.gov/pubmed/17303635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.128785
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