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Sphingosine Kinase-1 Associates with Integrin α(V)β(3) to Mediate Endothelial Cell Survival
Sphingosine kinase (SK)-1 promotes endothelial cell (EC) survival through the cell junction molecule CD31 (platelet endothelial cell adhesion molecule-1). The integrin α(v)β(3) is also essential for EC survival; inhibition of α(v)β(3) ligation promotes apoptosis. Herein we demonstrate that under bas...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Investigative Pathology
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2774083/ https://ncbi.nlm.nih.gov/pubmed/19815712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.090076 |
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