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Sphingosine kinase regulates the rate of endothelial progenitor cell differentiation

Circulating endothelial progenitor cells (EPCs) are incorporated into foci of neovascularization where they undergo differentiation to mature endothelial cells (ECs). We show here that the enzyme sphingosine kinase-1 (SK-1) regulates the rate and direction of EPC differentiation without effect on th...

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Detalhes bibliográficos
Main Authors: Bonder, Claudine S., Sun, Wai Y., Matthews, Tyson, Cassano, Carlos, Li, Xiaochun, Ramshaw, Hayley S., Pitson, Stuart M., Lopez, Angel F., Coates, P. Toby, Proia, Richard L., Vadas, Mathew A., Gamble, Jennifer R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651020/
https://ncbi.nlm.nih.gov/pubmed/19109558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-166942
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