Sphingosine kinase regulates the rate of endothelial progenitor cell differentiation

Circulating endothelial progenitor cells (EPCs) are incorporated into foci of neovascularization where they undergo differentiation to mature endothelial cells (ECs). We show here that the enzyme sphingosine kinase-1 (SK-1) regulates the rate and direction of EPC differentiation without effect on th...

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Autors principals: Bonder, Claudine S., Sun, Wai Y., Matthews, Tyson, Cassano, Carlos, Li, Xiaochun, Ramshaw, Hayley S., Pitson, Stuart M., Lopez, Angel F., Coates, P. Toby, Proia, Richard L., Vadas, Mathew A., Gamble, Jennifer R.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2009
Matèries:
Vascular Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651020/
https://ncbi.nlm.nih.gov/pubmed/19109558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-166942
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