Presenilins Are Enriched in Endoplasmic Reticulum Membranes Associated with Mitochondria

Presenilin-1 (PS1) and -2 (PS2), which when mutated cause familial Alzheimer disease, have been localized to numerous compartments of the cell, including the endoplasmic reticulum, Golgi, nuclear envelope, endosomes, lysosomes, the plasma membrane, and mitochondria. Using three complementary approac...

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Bibliografiske detaljer
Main Authors: Area-Gomez, Estela, de Groof, Ad J.C., Boldogh, Istvan, Bird, Thomas D., Gibson, Gary E., Koehler, Carla M., Yu, Wai Haung, Duff, Karen E., Yaffe, Michael P., Pon, Liza A., Schon, Eric A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2009
Fag:
Short Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774047/
https://ncbi.nlm.nih.gov/pubmed/19834068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.090219
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