Presenilins Are Enriched in Endoplasmic Reticulum Membranes Associated with Mitochondria

Presenilin-1 (PS1) and -2 (PS2), which when mutated cause familial Alzheimer disease, have been localized to numerous compartments of the cell, including the endoplasmic reticulum, Golgi, nuclear envelope, endosomes, lysosomes, the plasma membrane, and mitochondria. Using three complementary approac...

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Bibliografski detalji
Glavni autori: Area-Gomez, Estela, de Groof, Ad J.C., Boldogh, Istvan, Bird, Thomas D., Gibson, Gary E., Koehler, Carla M., Yu, Wai Haung, Duff, Karen E., Yaffe, Michael P., Pon, Liza A., Schon, Eric A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2009
Teme:
Short Communications
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774047/
https://ncbi.nlm.nih.gov/pubmed/19834068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.090219
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