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Presenilins Are Enriched in Endoplasmic Reticulum Membranes Associated with Mitochondria

Presenilin-1 (PS1) and -2 (PS2), which when mutated cause familial Alzheimer disease, have been localized to numerous compartments of the cell, including the endoplasmic reticulum, Golgi, nuclear envelope, endosomes, lysosomes, the plasma membrane, and mitochondria. Using three complementary approac...

詳細記述

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書誌詳細
主要な著者: Area-Gomez, Estela, de Groof, Ad J.C., Boldogh, Istvan, Bird, Thomas D., Gibson, Gary E., Koehler, Carla M., Yu, Wai Haung, Duff, Karen E., Yaffe, Michael P., Pon, Liza A., Schon, Eric A.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Investigative Pathology 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774047/
https://ncbi.nlm.nih.gov/pubmed/19834068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.090219
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