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Reconstitution of RNA exosomes from human and Saccharomyces cerevisiae: Cloning, expression, purification, and activity assays

Eukaryotic RNA exosomes participate in 3′-5′ processing and degradation of RNA in the nucleus and cytoplasm. RNA exosomes are multi-subunit complexes composed of at least nine distinct proteins which form the exosome core. While the eukaryotic exosome core shares structural and sequence similarity t...

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Detalhes bibliográficos
Main Authors: Greimann, Jaclyn C., Lima, Christopher D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773543/
https://ncbi.nlm.nih.gov/pubmed/19111177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0076-6879(08)02610-4
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