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Reconstitution of Human Necrosome Interactions in Saccharomyces cerevisiae

The necrosome is a large-molecular-weight complex in which the terminal effector of the necroptotic pathway, Mixed Lineage Kinase Domain-Like protein (MLKL), is activated to induce necroptotic cell death. The precise mechanism of MLKL activation by the upstream kinase, Receptor Interacting Serine/Th...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Ji, Y., Ward, L. A., Hawkins, C. J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7911209/
https://ncbi.nlm.nih.gov/pubmed/33503908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11020153
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