Peripheral blood T cells in acute myeloid leukemia (AML) patients at diagnosis have abnormal phenotype and genotype and form defective immune synapses with AML blasts

Understanding how the immune system in patients with cancer interacts with malignant cells is critical for the development of successful immunotherapeutic strategies. We studied peripheral blood from newly diagnosed patients with acute myeloid leukemia (AML) to assess the impact of this disease on t...

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Hauptverfasser: Le Dieu, Rifca, Taussig, David C., Ramsay, Alan G., Mitter, Richard, Miraki-Moud, Faridah, Fatah, Rewas, Lee, Abigail M., Lister, T. Andrew, Gribben, John G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2009
Schlagworte:
Myeloid Neoplasia
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773481/
https://ncbi.nlm.nih.gov/pubmed/19710498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-02-206946
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