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Localised and reversible TGFβ signalling switches breast cancer cells from cohesive to single cell motility

Here we use intravital imaging to demonstrate a reversible transition to a motile state as breast cancer cells spread. Imaging primary tumours reveals heterogeneity in cell morphology and motility. Two distinct modes of motility are observed: collective and single-celled. By monitoring the localisat...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Giampieri, Silvia, Manning, Cerys, Hooper, Steven, Jones, Louise, Hill, Caroline S., Sahai, Erik
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773241/
https://ncbi.nlm.nih.gov/pubmed/19838175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1973
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