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Localised and reversible TGFβ signalling switches breast cancer cells from cohesive to single cell motility
Here we use intravital imaging to demonstrate a reversible transition to a motile state as breast cancer cells spread. Imaging primary tumours reveals heterogeneity in cell morphology and motility. Two distinct modes of motility are observed: collective and single-celled. By monitoring the localisat...
שמור ב:
| Main Authors: | , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2009
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2773241/ https://ncbi.nlm.nih.gov/pubmed/19838175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1973 |
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