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Localised and reversible TGFβ signalling switches breast cancer cells from cohesive to single cell motility
Here we use intravital imaging to demonstrate a reversible transition to a motile state as breast cancer cells spread. Imaging primary tumours reveals heterogeneity in cell morphology and motility. Two distinct modes of motility are observed: collective and single-celled. By monitoring the localisat...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2773241/ https://ncbi.nlm.nih.gov/pubmed/19838175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1973 |
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