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TGF-β family ligands exhibit distinct signalling dynamics that are driven by receptor localisation

Growth factor-induced signal transduction pathways are tightly regulated at multiple points intracellularly, but how cells monitor levels of extracellular ligand and translate this information into appropriate downstream responses remains unclear. Understanding signalling dynamics is thus a key chal...

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Publicat a:J Cell Sci
Autors principals: Miller, Daniel S. J., Schmierer, Bernhard, Hill, Caroline S.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679586/
https://ncbi.nlm.nih.gov/pubmed/31217285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.234039
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