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Regulation of LKB1/STRAD localization and function by E-cadherin
LKB1 kinase is a tumor suppressor that is causally linked to Peutz-Jeghers (PJS) syndrome [1]. In complex with the pseudokinase STRAD and the scaffolding protein MO25, LKB1 phosphorylates and activates AMPK family kinases, which mediate many cellular processes [2, 3]. The prototypical family member...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2773019/ https://ncbi.nlm.nih.gov/pubmed/19110428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.11.033 |
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