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The LKB1 complex-AMPK pathway: the tree that hides the forest
Initially identified as the Caenorhabditis elegans PAR-4 homologue, the serine threonine kinase LKB1 is conserved throughout evolution and ubiquitously expressed. In humans, LKB1 is causally linked to the Peutz-Jeghers syndrome (PJS) and is one of the most commonly mutated genes in several cancers l...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Springer
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3530433/ https://ncbi.nlm.nih.gov/pubmed/21656073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-011-9457-7 |
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