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The LKB1 complex-AMPK pathway: the tree that hides the forest

Initially identified as the Caenorhabditis elegans PAR-4 homologue, the serine threonine kinase LKB1 is conserved throughout evolution and ubiquitously expressed. In humans, LKB1 is causally linked to the Peutz-Jeghers syndrome (PJS) and is one of the most commonly mutated genes in several cancers l...

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Bibliografske podrobnosti
Main Authors: Sebbagh, Michael, Olschwang, Sylviane, Santoni, Marie-Josée, Borg, Jean-Paul
Format: Artigo
Jezik:Inglês
Izdano: Springer 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530433/
https://ncbi.nlm.nih.gov/pubmed/21656073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10689-011-9457-7
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