Glutathione Peroxidase 4 Differentially Regulates the Release of Apoptogenic Proteins from Mitochondria

Glutathione peroxidase 4 (Gpx4) is a unique antioxidant enzyme that repairs oxidative damage to biomembranes. In the present study, we examined the effect of Gpx4 on the release of various apoptogenic proteins from mitochondria using transgenic mice overexpressing Gpx4 [Tg(GPX4(+/0))] and mice defic...

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Detalhes bibliográficos
Main Authors: Liang, Hanyu, Ran, Qitao, Jang, Youngmok Charles, Holstein, Deborah, Lechleiter, James, McDonald-Marsh, Tiffany, Musatov, Andrej, Song, Wook, Remmen, Holly Van, Richardson, Arlan
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773016/
https://ncbi.nlm.nih.gov/pubmed/19447173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.05.012
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