Glutathione Peroxidase 4 Differentially Regulates the Release of Apoptogenic Proteins from Mitochondria

Glutathione peroxidase 4 (Gpx4) is a unique antioxidant enzyme that repairs oxidative damage to biomembranes. In the present study, we examined the effect of Gpx4 on the release of various apoptogenic proteins from mitochondria using transgenic mice overexpressing Gpx4 [Tg(GPX4(+/0))] and mice defic...

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Hlavní autoři: Liang, Hanyu, Ran, Qitao, Jang, Youngmok Charles, Holstein, Deborah, Lechleiter, James, McDonald-Marsh, Tiffany, Musatov, Andrej, Song, Wook, Remmen, Holly Van, Richardson, Arlan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773016/
https://ncbi.nlm.nih.gov/pubmed/19447173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.05.012
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