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Suppression of Atherogenesis by Overexpression of Glutathione Peroxidase-4 in Apolipoprotein E-Deficient Mice

Accumulation of oxidized lipids in the arterial wall contributes to atherosclerosis. Glutathione peroxidase-4 (GPx4) is a hydroperoxide scavenger that removes oxidative modifications from lipids such as free fatty acids, cholesterols, and phospholipids. Here, we set out to assess the effect of GPx4...

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Detalhes bibliográficos
Main Authors: Guo, ZhongMao, Ran, Qitao, Roberts, L. Jackson, Zhou, Lichun, Richardson, Arlan, Sharan, Chakradhari, Wu, DongFan, Yang, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2245803/
https://ncbi.nlm.nih.gov/pubmed/18215741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2007.09.009
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