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Short Form Glutathione Peroxidase 4 Is the Essential Isoform Required for Survival and Somatic Mitochondrial Functions

Glutathione peroxidase 4 (Gpx4) is an essential antioxidant enzyme having multiple functions. A long form Gpx4 protein and a short form Gpx4 protein, which are distinguishable by the presence or lack of a mitochondrial signal peptide at the N terminus, are generated from the Gpx4 gene. In this study...

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Detalhes bibliográficos
Main Authors: Liang, Hanyu, Yoo, Si-Eun, Na, Ren, Walter, Christi A., Richardson, Arlan, Ran, Qitao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781482/
https://ncbi.nlm.nih.gov/pubmed/19744930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.032839
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